(S)-1, 2, 3, 4-tetrahydro-3-isoquinolinecarboxylic acid (for Quinapril)

Name	L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Synonyms	(S)-TIC L-Tic-OH L-1,2,3,4-Tetrahydro 4-Tetrahydro-3-Isoquinolinecarboxylic acid L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid S-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [S]-1,2,3,4-Tetrahydro-3-Isoquinolingcarboxylic Acid (S)-1,2,3,4-Tetrahydro-3-isoquinoline-carboxylic acid (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (S)-N-tert-1,2,3,4-tetrahydroisoquinoline -3-carboxamide (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid (S)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID METHYLESTHER (S)-1, 2, 3, 4-tetrahydro-3-isoquinolinecarboxylic acid (for Quinapril)
CAS	74163-81-8
EINECS	616-058-0
InChI	InChI=1/C10H11NO2.ClH/c12-10(13)9-5-7-3-1-2-4-8(7)6-11-9;/h1-4,9,11H,5-6H2,(H,12,13);1H/t9-;/m0./s1
InChIKey	BWKMGYQJPOAASG-VIFPVBQESA-N

Molecular Formula	C10H11NO2
Molar Mass	177.2
Density	1.1607 (rough estimate)
Melting Point	>300°C(lit.)
Boling Point	309.12°C (rough estimate)
Specific Rotation(α)	-157.4 º (24 ºC)
Flash Point	193.2°C
Vapor Presure	5.62E-07mmHg at 25°C
Appearance	White to Light Yellow Crystal
Color	White to Almost white
BRN	4842199
pKa	2.21±0.20(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Refractive Index	-166 ° (C=1, 1mol/L
MDL	MFCD00144533
Use	Used as a drug Intermediate

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
HS Code	29334900

Introduction	(S)-(-)-1,2,3, 4-tetrahydroisoquinoline-3-carboxylic acid is a quinoline derivative and is used as an intermediate for the synthesis of quinapril. Quinapril is a product developed by Pfizer and approved by the US FDA in 1991 for hypertension, congestive heart failure and angioedema.
Use	for use as a pharmaceutical intermediate Quinapril intermediate.

Last Update：2024-04-09 21:54:55

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Product Name: L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Request for quotation
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(S)-1, 2, 3, 4-tetrahydro-3-isoquinolinecarboxylic acid (for Quinapril) Request for Quotation